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CNI Movement Disorders Center
Research & Outcomes
Parkinson's Disease Studies
STUDY: Study of an oral medication vs. placebo in patients with motor fluctuations
Primary Investigator: Rajeev Kumar, MD
MD Coordinator: Breanna Nickels
Contact: 303-357-5445 | bnickels@thecni.org
Site: CNI, 701 E. Hampden Ave. Suite 510, Englewood, Colorado 80113
PURPOSE: To show that at least 5mg twice daily of study medication is superior to placebo, proven by a reduction of “off” time
ELIGIBILITY:
- Subjects must be between the ages of 30-85
- Must have received prior therapy with L-dopa for approximately 2 or more years
- Must be experiencing a minimum of 2 hours/day of “off” time
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STUDY: A 12-week, double-blind, placebo-controlled study to explore the efficacy and safety of an oral medication when combined with increased doses of L-dopa in patients with OFF time and moderate-severe L-dopa induced dyskinesia.
Investigator: Rajeev Kumar, MD
MD Coordinator: Brenna Nickels
Contact: 303-357-5445 | bnickels@thecni.org
Site: Colorado Neurological Institute, 701 E. Hampden Ave. Suite 510, Englewood, Colorado 80113
PURPOSE: This 12-week study will evaluate whether the use of this oral medication can increase the therapeutic window of L-dopa in patients whose control of their Parkinson’s disease symptoms is limited by the development of dyskinesias when higher dose of L-dopa are used.
ELIGIBILITY:
- Male or female subjects aged 30-80 year old
- Presence of Levodopa-Induced dyskinesias > 25% of the waking day
- At least 3 hrs of “off” time per day
- Must be on Levodopa (Sinemet)
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STUDY: Self-Efficacy Learning Program for Recently Diagnosed Parkinson's Patients
Primary Investigator: Rajeev Kumar, MD
Research Coordinator: Keith Gryder, CRCC
Contact: 303.783.4974| kgryder@thecni.org
Site: CNI, 701 E. Hampden Ave. Suite 510, Englewood, Colorado 80113
PURPOSE: To determine whether the teaching of self-efficacy skills to patients recently diagnosed with Parkinson's disease in monthly support group meetings over a 12-month period will result in better physical and emotional functioning, better quality of life, and more self-efficacy after 12 months.
ELIGIBILITY:
- Diagnosed with Parkinson's disease within 3 years
- Between ages 30-80
- Live within 90 minutes of the south Denver metro area
- Have not previously participated in a Parkinson's support group
>>Huntington's Disease Studies
>>Progressive Supranuclear Palsy Studies
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