headacheHead Pain Studies

If you think you may qualify for one of these studies, please contact CNI’s Research Department at 303-806-7423.

 

 

Cluster Headaches:
This headache syndrome involves what is described as “attacks” of severe pain on one side of the head lasting 15-180 minutes and occurring as little as once every day or as often as 8 times a day. Attacks are associated with eye redness, tearing from the eye, runny nose, nasal congestion, facial sweating, or sometimes eyelid swelling, all occurring on one side. Cluster headaches generally start occurring between the ages of 30-40 years of age and tend to be more common in men. Given their intermittent nature, these types of headaches can create significant anxiety due to anticipation of when the next “attack” may occur. (credit: www.coloradoheadache.com)

CNI Cluster Headache Research Studies Open to Enrollment:

1) Protocol I5Q-MC-CGAL/M(c) – A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of LY2951742 in Patients with Episodic/Chronic Cluster Headache

Primary Investigator: Cori Millen, DO

Cluster Lilly Brochure

2) TV48125-CNS-30056/7 – A Multicenter, Randomized, Double-Blink, Double-Dummy, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of 2 Dose Regimens (Intravenous/Subcutaneous and Subcutaneous) of TEV-48125 versus Placebo for the Prevention of Episodic/Chronic Cluster Headache

Primary Investigator: Cori Millen, DO

Cluster Teva Brochure

 

Migraine Headaches

This headache syndrome involves what is described as an intense pulsing or throbbing pain in one area of the head. Part of the criteria of diagnosing a migraine is by its pain and the number of attacks, as well as additional symptoms including nausea and/or vomiting or sensitivity to both light and sound. Migraine is three times more common in women than in men and affects more than 10% of people worldwide. Roughly 1/3 of affected individuals can predict the onset of a migraine because is it preceded by an “aura.” An aura can be a visual disturbance that appears as flashing lights, zig-zag lines or a temporary loss of vision. It can also include sensory or speech disturbances. (credit: www.coloradoheadache.com)

 

CNI Migraine Headache Research Studies Open to Enrollment:

1) Protocol URB-MD-02 – A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Single Attack Study to Evaluate the Efficacy, Safety and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine

Primary Investigator: Cori Millen, DO

Migraine Allergan Brochure

Colorado Neurological Insitute